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Complete relief of CRPS-associated pain during magnesium infusion in a patient with postpartum preeclampsia
  1. Jonathan A Niconchuk and
  2. Michael G Richardson
  1. Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, Tennessee, USA
  1. Correspondence to Dr Michael G Richardson, Division of Obstetric Anesthesiology, Vanderbilt University Medical Center, Nashville, TN 37232, USA; michael.g.richardson{at}


A pregnant patient with chronic regional pain syndrome (CRPS) and indwelling spinal cord stimulator presented with twin gestation for induction of preterm labor due to preeclampsia. Intravenous magnesium was initiated and a lumbar epidural catheter was placed uneventfully for labor analgesia. The patient reported complete relief of her CRPS-associated pain during and for 24 hours after delivery, while receiving intravenous magnesium, with her pain symptoms returning shortly after discontinuing magnesium. To our knowledge, there are no case reports that describe CRPS-associated pain relief while on peripartum magnesium therapy.

  • chronic regional pain syndrome
  • pregnancy
  • magnesium

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  • Presented at This report was presented in part at the 2018 annual meeting of the Society for Obstetric Anesthesia and Perinatology in Miami Beach, 9–13 May 2018.

  • Contributors JAN and MGR collaboratively researched, wrote, revised, and finalized this manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.