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Local anesthetic resistance in a Crohn’s patient undergoing cesarean delivery
  1. Soleil S Schutte and
  2. Tammy Euliano
  1. Anesthesiology, University of Florida, Gainesville, Florida, USA
  1. Correspondence to Dr Tammy Euliano, Anesthesiology, University of Florida, Gainesville, FL 32610, USA; teuliano{at}


Introduction Patient resistance to local anesthetics is rarely considered as the cause of regional anesthesia failure.

Case report We report a case of resistance to local anesthetics in a patient with Crohn’s disease who underwent cesarean section under continuous spinal anesthesia.

Discussion Resistance to local anesthetics may be more common than we think, especially among patients with chronic pain. Providers should consider local anesthetic resistance when regional anesthesia is unsuccessful. Further research is needed to determine if skin wheal tests and/or a different local anesthetic could improve results.

  • anesthesia, local
  • obstetrics
  • injections, spinal
  • acute pain

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  • Contributors SSS: collection and analysis of data and writing and editing of the manuscript. TE: collection and analysis of data and writing and editing of the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.