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Novel compound LL-a produces long and nociceptive-selective regional anesthesia via TRPV1 channels in rodents sciatic nerve block model

Authors

  • Cheng Zhou Laboratory of Anesthesia & Critical Care Medicine, Translational Neuroscience Center, National Clinical Research Center for Geriatrics, National-Local Joint Engineering Research Center of Translational Medicine of Anesthesiology, West China Hospital of Sichuan University, Chengdu, Sichuan, China Department of Anesthesiology, West China Hospital of Sichuan University, Chengdu, Sichuan, China PubMed articlesGoogle scholar articles
  • Lei Tang Laboratory of Anesthesia & Critical Care Medicine, Translational Neuroscience Center, National Clinical Research Center for Geriatrics, National-Local Joint Engineering Research Center of Translational Medicine of Anesthesiology, West China Hospital of Sichuan University, Chengdu, Sichuan, China Department of Anesthesiology, West China Hospital of Sichuan University, Chengdu, Sichuan, China PubMed articlesGoogle scholar articles
  • Qinqin Yin Laboratory of Anesthesia & Critical Care Medicine, Translational Neuroscience Center, National Clinical Research Center for Geriatrics, National-Local Joint Engineering Research Center of Translational Medicine of Anesthesiology, West China Hospital of Sichuan University, Chengdu, Sichuan, China Department of Anesthesiology, West China Hospital of Sichuan University, Chengdu, Sichuan, China PubMed articlesGoogle scholar articles
  • Linghui Yang Laboratory of Anesthesia & Critical Care Medicine, Translational Neuroscience Center, National Clinical Research Center for Geriatrics, National-Local Joint Engineering Research Center of Translational Medicine of Anesthesiology, West China Hospital of Sichuan University, Chengdu, Sichuan, China PubMed articlesGoogle scholar articles
  • Deying Gong Laboratory of Anesthesia & Critical Care Medicine, Translational Neuroscience Center, National Clinical Research Center for Geriatrics, National-Local Joint Engineering Research Center of Translational Medicine of Anesthesiology, West China Hospital of Sichuan University, Chengdu, Sichuan, China PubMed articlesGoogle scholar articles
  • Yi Kang Laboratory of Anesthesia & Critical Care Medicine, Translational Neuroscience Center, National Clinical Research Center for Geriatrics, National-Local Joint Engineering Research Center of Translational Medicine of Anesthesiology, West China Hospital of Sichuan University, Chengdu, Sichuan, China PubMed articlesGoogle scholar articles
  • Hangxue Cao Laboratory of Anesthesia & Critical Care Medicine, Translational Neuroscience Center, National Clinical Research Center for Geriatrics, National-Local Joint Engineering Research Center of Translational Medicine of Anesthesiology, West China Hospital of Sichuan University, Chengdu, Sichuan, China PubMed articlesGoogle scholar articles
  • Jing Fan Laboratory of Anesthesia & Critical Care Medicine, Translational Neuroscience Center, National Clinical Research Center for Geriatrics, National-Local Joint Engineering Research Center of Translational Medicine of Anesthesiology, West China Hospital of Sichuan University, Chengdu, Sichuan, China PubMed articlesGoogle scholar articles
  • Yujun Zhang Laboratory of Anesthesia & Critical Care Medicine, Translational Neuroscience Center, National Clinical Research Center for Geriatrics, National-Local Joint Engineering Research Center of Translational Medicine of Anesthesiology, West China Hospital of Sichuan University, Chengdu, Sichuan, China Department of Anesthesiology, West China Hospital of Sichuan University, Chengdu, Sichuan, China PubMed articlesGoogle scholar articles
  • Duo Qian Laboratory of Anesthesia & Critical Care Medicine, Translational Neuroscience Center, National Clinical Research Center for Geriatrics, National-Local Joint Engineering Research Center of Translational Medicine of Anesthesiology, West China Hospital of Sichuan University, Chengdu, Sichuan, China PubMed articlesGoogle scholar articles
  • Qianqian Zhang Laboratory of Anesthesia & Critical Care Medicine, Translational Neuroscience Center, National Clinical Research Center for Geriatrics, National-Local Joint Engineering Research Center of Translational Medicine of Anesthesiology, West China Hospital of Sichuan University, Chengdu, Sichuan, China PubMed articlesGoogle scholar articles
  • Bowen Ke Laboratory of Anesthesia & Critical Care Medicine, Translational Neuroscience Center, National Clinical Research Center for Geriatrics, National-Local Joint Engineering Research Center of Translational Medicine of Anesthesiology, West China Hospital of Sichuan University, Chengdu, Sichuan, China Department of Anesthesiology, West China Hospital of Sichuan University, Chengdu, Sichuan, China PubMed articlesGoogle scholar articles
  • Jin Liu Laboratory of Anesthesia & Critical Care Medicine, Translational Neuroscience Center, National Clinical Research Center for Geriatrics, National-Local Joint Engineering Research Center of Translational Medicine of Anesthesiology, West China Hospital of Sichuan University, Chengdu, Sichuan, China Department of Anesthesiology, West China Hospital of Sichuan University, Chengdu, Sichuan, China PubMed articlesGoogle scholar articles
  • Wensheng Zhang Laboratory of Anesthesia & Critical Care Medicine, Translational Neuroscience Center, National Clinical Research Center for Geriatrics, National-Local Joint Engineering Research Center of Translational Medicine of Anesthesiology, West China Hospital of Sichuan University, Chengdu, Sichuan, China Department of Anesthesiology, West China Hospital of Sichuan University, Chengdu, Sichuan, China PubMed articlesGoogle scholar articles
  • Jun Yang Laboratory of Anesthesia & Critical Care Medicine, Translational Neuroscience Center, National Clinical Research Center for Geriatrics, National-Local Joint Engineering Research Center of Translational Medicine of Anesthesiology, West China Hospital of Sichuan University, Chengdu, Sichuan, China PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Jun Yang, Laboratory of Anaesthesia & Critical Care Medicine, Translational Neuroscience Center, National Clinical Research Center for Geriatrics,National-Local Joint Engineering Research Center of Translational Medicine of Anesthesiology, Sichuan University West China Hospital, Chengdu 610041, China; yang215jun{at}163.com; Professor Wensheng Zhang, Laboratory of Anaesthesia & Critical Care Medicine, Translational Neuroscience Center, National Clinical Research Center for Geriatrics,National-Local Joint Engineering Research Center of Translational Medicine of Anesthesiology, Sichuan University West China Hospital, Chengdu,610041, China; zhang_ws{at}scu.edu.cn
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Citation

Zhou C, Tang L, Yin Q, et al
Novel compound LL-a produces long and nociceptive-selective regional anesthesia via TRPV1 channels in rodents sciatic nerve block model

Publication history

  • Received October 8, 2019
  • Revision received March 17, 2020
  • Accepted March 19, 2020
  • First published April 12, 2020.
Online issue publication 
May 20, 2020

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