Statistics from Altmetric.com
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.
Contributors HST contributed to patient recruitment, data analysis and interpretation, and wrote the manuscript. CWT contributed to study design, data management, analysis and interpretation, and wrote the manuscript. RS contributed to study design and performed data analysis and interpretation. MS and WLL contributed to patient recruitment and data management. DDS contributed to study design, patient recruitment, and data analysis and interpretation. ATHS contributed to study design and data analysis and interpretation. BLS planned and oversaw the study, including patient recruitment, study design, data analysis and interpretation, and manuscript writing.
Funding This work was supported by funding from the National Medical Research Council Clinical Trials Grant - Investigator-Initiated Trials (grant no. CTG13feb013). The aforementioned sponsor was not involved in the study activities.
Competing interests None declared.
Patient consent for publication Not required.
Ethics approval The study was approved by the SingHealth Centralized Institutional Review Board, Singapore (SingHealth CIRB Ref: 2014/670/D or 2018/3128). This work was conducted in accordance with the Declaration of Helsinki.
Provenance and peer review Not commissioned; externally peer reviewed.