Background and Objectives Interpleural analgesia was used in a case of esophageal perforation due to surgical mishap. The medical literature cites no reference to use of this technique in this condition.

Method Interpleural bupivacaine analgesia was used along with conventional forms of pain relief.

Results Superior analgesia was obtained, and the method proved to be safe and complication free on a general surgical ward over the period of several days that it was used.

Conclusion Interpleural analgesia is safe and effective for management of pain due to esophageal perforation.