Although generally considered competitive, the alkenylation and carbonyl olefination routes
to alkenes are also complementary. In this Account, we focus on these approaches for the …

The field of digital fashion is rapidly evolving, yet what constitutes digital fashion, and how it
should be defined has not been firmly established. This study aims to conceptualize and …

The mechanism of apoptosis has been extensively characterized over the past decade, but
little is known about alternative forms of regulated cell death. Although stimulation of the …

NITRIC oxide (NO), a potent vasodilator produced by endothelial cells, is thought to be the
endothelium-dependent relaxing factor (EDRF) which mediates vascular relaxation in …

The proposal that nitric oxide (NO) or its reactant products mediate toxicity in brain remains
controversial in part because of the use of nonselective agents that block NO formation in …

Although the trigeminal nerve innervates the meninges and participates in the genesis of
migraine headaches, triggering mechanisms remain controversial and poorly understood …

The treatment of ischemic strokes is limited to prophylactic agents that block the coagulation
cascade. Here, we show that cholesterol-lowering agents, 3-hydroxy-3-methylglutaryl (HMG) …

The interleukin 1β converting enzyme (ICE) family plays a pivotal role in programmed cell
death and has been implicated in stroke and neurodegenerative diseases. During …

Abstract Phospholipase A2 (PLA2) enzymes are critical regulators of prostaglandin and
leukotriene synthesis and can directly modify the composition of cellular membranes,. PLA2 …

Mitochondrial permeability transition (PT) is a phenomenon induced by high levels of matrix
calcium and is characterized by the opening of the PT pore (PTP). Activation of the PTP …