The epidemiology of chronic kidney disease. The world's disease profile is changing, and
chronic diseases now account for the majority of global morbidity and mortality, rather than …

The International Diabetes Federation predicts that the number of people with diabetes in
the world will rise from 194 million today to 333 million in 2025 [1]. The next 25–50 years will …

In 2003, the International Society of Nephrology and the International Diabetes Federation
launched a booklet called 'Diabetes in the Kidney: Time to act'[1] to highlight the global …

Background It is unknown whether either the angiotensin-II–receptor blocker irbesartan or
the calcium-channel blocker amlodipine slows the progression of nephropathy in patients …

The incidence of ESRD is increasing dramatically. Progression to end-stage may be halted
or slowed when kidney damage is detected at an early stage. Kidney damage is frequently …

OBJECTIVE—To determine the population-based prevalence of diabetes and other
categories of glucose intolerance (impaired glucose tolerance [IGT] and impaired fasting …

Transforming growth factor-β regulates tubular epithelial-myofibroblast transdifferentiation in
vitro. Background We recently found evidence of tubular epithelial-myofibroblast …

Macrophages in mouse type 2 diabetic nephropathy: Correlation with diabetic state and
progressive renal injury. Background Macrophage-mediated renal injury has been …

Background Recurrent glomerulonephritis is a known cause of renal allograft loss; however,
the incidence of this complication is poorly defined. We determined the incidence, timing …

Tubulointerstitial disease, a prominent phenomenon in diabetic nephropathy, correlates with
decline in renal function. The underlying pathogenic link between chronic hyperglycemia …