The goal of treatment in patients with complex regional pain syndrome (CRPS) is to improve
function, relieve pain, and achieve remission. Current guidelines recommend …

Intraspinal drug infusion using fully implantable pump and catheter systems is a safe and
effective therapy for selected patients with chronic pain. The options for this approach are …

PURPOSE: Implantable intrathecal drug delivery systems (IDDSs) have been used to
manage refractory cancer pain, but there are no randomized clinical trial (RCT) data …

Neuropathic pain is a considerable burden that affects activities of daily living. The
management of neuropathic pain can be challenging because of multiple etiologies and …

Safety and efficacy data from a study of slow intrathecal (IT) ziconotide titration for the
management of severe chronic pain are presented. Patients randomized to ziconotide (n …

Background Intraspinally administered alpha 2-adrenergic agonists may relieve pain in
sympathetically maintained pain (SMP) syndromes, such as reflex sympathetically dystrophy …

Background: Chronic persistent pain as a result of terminal illness, either as a consequence
of the disease or the necessary treatment, is common in patients with cancer. For these …

The present study evaluated the safety and efficacy of patient-activated delivery of
intrathecal morphine sulfate boluses delivered by way of a novel internalized intrathecal …

Background and objectives: Breakthrough cancer pain (BTcP) represents an important
clinical challenge in the care of patients with cancer. This trial evaluated the efficacy and …

Methods One hundred nineteen patients with a 1 to 5-year history of pain attributed to
diabetic neuropathy and a score of≥ 4 on the Likert pain scale entered the multicenter …