The solubility of 49 metal-containing compounds and 15 “free” ligands in supercritical fluid
carbon dioxide is reviewed. Solubilities were found to range over eight orders of magnitude …

Of paramount importance for the development of cell therapies to treat diabetes is the
production of sufficient numbers of pancreatic endocrine cells that function similarly to …

Abstract Development of a cell therapy for diabetes would be greatly aided by a renewable
supply of human β-cells. Here we show that pancreatic endoderm derived from human …

A direct measurement of the pH of water in contact with supercritical CO2 was made by
observing the spectra of a pH indicator with a UV-vis spectrophotometer. The pH was …

Metal ions in solid and liquid materials can be extracted by supercritical CO2 containing a
suitable ligand. Fluorine substituted ligands are particularly effective because of the high …

Despite their low frequency, plasmacytoid dendritic cells (pDCs) produce most of the type I
IFN that is detectable in the blood following viral infection. The endosomal Toll-like receptors …

Identification of endogenous signals that regulate expansion and maturation of organ-
specific progenitor cells is a major goal in studies of organ development. Here we provide …

While the research and industrial communities are wholehartedly embracing the use of
supercritical fluid extraction (SFE) technology, little has been written about it in …

Identification of signaling pathways that maintain and promote adult pancreatic islet
functions will accelerate our understanding of organogenesis and improve strategies for …

The feasibility of using Kelex 100, Cyanex 272, 301 and 302, and D2EHTPA as reagents for
the supercritical fluid extraction of toxic heavy metals is demonstrated. High extraction …