In contrast with the short research history of the enzymatic synthesis of nitric oxide (NO), the
introduction of nitrate‐containing compounds for medicinal purposes marked its 150th …

To assess the hemodynamic properties of the new inhalational anesthetic sevoflurane, 22
dogs were chronically instrumented for measurement of heart rate, aortic, left ventricular and …

Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in a global pandemic with …

Hemorrhagic shock (HS) and trauma is currently the leading cause of death in young adults
worldwide. Morbidity and mortality after HS and trauma is often the result of multi-organ …

Background: Clinical studies have shown that resuscitation with fresh frozen plasma (FFP) is
associated with improved outcome after severe hemorrhagic shock (HS). We hypothesized …

During hypoxia or inflammation, extracellular adenosine levels are elevated. Studies using
pharmacologic approaches or genetic animal models pertinent to extracellular adenosine …

Seven mongrel dogs were chronically instrumented for the measurement of aortic and left
ventricular blood pressures, cardiac output, left ventricular wall thickening, left ventricular …

Purpose: To assess the role of esmolol, a β 1 receptor blocker, in the modulation of pain in
the absence of anesthesia. Methods: Rats were chronically instrumented to record mean …

To compare the effects of sevoflurane and isoflurane on hepatic circulation, eighteen dogs
were chronically instrumented for measurements of mean aortic blood pressure and cardiac …

Background Neuroinflammation plays a key role in PD pathogenesis, and allogeneic bone
marrow–derived mesenchymal stem cells can be used as an immunomodulatory therapy …