Effects of obstetric analgesics and anesthetics on the neonate: a review

JE Mattingly, J D'Alessio, J Ramanathan - Pediatric Drugs, 2003 - Springer
Most anesthetic and analgesic agents in current use traverse the placental barrier in varying
degrees, but are well tolerated by the fetus if judiciously administered. For labor analgesia …

The use of labetalol for attenuation of the hypertensive response to endotracheal incubation in preeclampsia

J Ramanathan, BM Sibai, WC Mabie… - American journal of …, 1988 - Elsevier
Twenty-five women with preeclampsia who were scheduled to undergo cesarean section
under general anesthesia were randomly assigned to either a labetalol pretreatment group …

Pre-eclampsia: fluids, drugs, and anesthetic management

J Ramanathan, K Bennett - … Clinics of North …, 2003 - anesthesiology.theclinics.com
Hypertensive disorders are the most common complications of pregnancy. They occur in 6%
to 8% of pregnancies and account for approximately 15% of maternal deaths in the United …

Anesthetic Modification of Hernodynamic and Neuroendocrine Stress Responses to Cesarean Delivery in Women With Severe Preeclampsia

J Ramanathan, P Coleman, B Sibai - Anesthesia & Analgesia, 1991 - journals.lww.com
We conducted a prospective evaluation of the comparative effects of lumbar epidural and
general anesthesia on the hemodynamic and neuroendocrine stress response to cesarean …

Combined spinal and epidural anesthesia with low doses of intrathecal bupivacaine in women with severe preeclampsia: a preliminary report

J Ramanathan, AK Vaddadi, KL Arheart - Regional anesthesia and pain …, 2001 - Elsevier
Background and Objectives: The purpose of our study was to evaluate the quality of
anesthesia for cesarean delivery (CD), analgesia for labor (LA), hemodynamic changes, and …

The case for magnesium sulfate in preeclampsia-eclampsia

BM Sibai, J Ramanathan - International Journal of Obstetric Anesthesia, 1992 - Elsevier
Preeclampsia-eclampsia is a syndrome of unknown etiology that is unique to human
pregnancy. During the past century, numerous theories regarding its etiology have been …

Neuromuscular transmission studies in preeclamptic women receiving magnesium sulfate

J Ramanathan, BM Sibai, R Pillai, JJ Angel - American journal of obstetrics …, 1988 - Elsevier
The purpose of the study was to evaluate the neuromuscular transmission defect in
preeclamptic women receiving intravenous magnesium sulfate and to study the correlation …

The pharmacokinetics and maternal and neonatal effects of epidural lidocaine in preeclampsia

J Ramanathan, M Bottorff, JN Jeter, M Khalil… - Anesthesia & …, 1986 - journals.lww.com
The pharmacokinetics and maternal and neonatal effects of epidural lidocaine were
compared in ten preeclamptic and five normotensive women undergoing cesarean section …

Changes in maternal middle cerebral artery blood flow velocity associated with general anesthesia in severe preeclampsia

J Ramanathan, JJ Angel, AJ Bush… - Anesthesia & …, 1999 - journals.lww.com
In women with severe preeclampsia, significant increases in mean arterial pressures (MAP)
are common after rapid induction of general anesthesia (GA) and tracheal intubation. The …

Effects of maternal anesthesia in the neonate

JG D'Alessio, J Ramanathan - Seminars in perinatology, 1998 - Elsevier
All commonly used anesthetic agents and drugs undergo placental transfer. Understanding
the placental transfer of anesthetic drugs and their effects on the neonate is essential for …