We compared intrathecal ropivacaine to bupivacaine in patients scheduled for transurethral
resection of bladder or prostate. Doses of ropivacaine and bupivacaine were chosen …

It has been suggested that nasal administration of ketamine may be used to induce
anaesthesia in paediatric patients. We have examined the pharmacokinetics of ketamine …

Ketamine and midazolam can produce analgesia following intrathecal administration in
rabbits. However, neurotoxicity studies are required before these agents can be considered …

Background Although ketamine has been administered spinally in humans, previous
neurotoxicity studies have shown that it can induce spinal cord lesions in various animal …

Background The effects of volume and baricity of spinal bupivacaine on block onset, height,
duration, and hemodynamics were studied. Methods Ninety patients undergoing endoscopic …

Midazolam is used frequently for premedication in children, preferably by non-parenteral
administration. We have compared plasma concentrations of midazolam after nasal, rectal …

We report a study performed to compare the time and plasma drug concentrations
necessary to achieve a similar state of sedation after midazolam premedication given by …

We used a double-blind design to study urodynamic changes induced by [micro sign]-
agonists (fentanyl, morphine), a partial [micro sign]-agonist antagonist (buprenorphine), a …

After administration of doses ranging from 0.025 to 0.25 mg/kg, the neuromuscular blocking
effect of cisatracurium was assessed in 119 adult surgical patients receiving N 2 O-opioid …

Background and Objectives. A rabbit chronic model has been developed for investigation of
epidural anesthesia without surgery. Methods. A catheter was implanted via a nontraumatic …