Mechanisms linking obesity with cardiovascular disease

LF Van Gaal, IL Mertens, CE De Block - Nature, 2006 - nature.com
Obesity increases the risk of cardiovascular disease and premature death. Adipose tissue
releases a large number of bioactive mediators that influence not only body weight …

Obesity, haemostasis and the fibrinolytic system

I Mertens, LFV Gaal - Obesity reviews, 2002 - Wiley Online Library
Obese patients are at risk for the development of cardiovascular diseases, which can in part
be explained by disturbances in the haemostatic and fibrinolytic systems. Indeed, obese …

Overweight, obesity, and blood pressure: the effects of modest weight reduction

IL Mertens, LF Van Gaal - Obesity research, 2000 - Wiley Online Library
Several large epidemiological studies have shown an association between body mass
index and blood pressure in normal weight and overweight patients. Weight gain in adult life …

Reduction of the plasma concentration of C-reactive protein following nine months of endurance training

…, B Dufaux, O Heine, I Mertens… - … journal of sports …, 2000 - thieme-connect.com
Accepted after revision: July 10, 1999 ssss An intense physical exercise induces an
inflammatory reaction as demonstrated by the delayed increase in blood of acute phase …

Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles

…, M Lenassi, J Leivo, I Mertens… - Journal of …, 2021 - Wiley Online Library
Urine is commonly used for clinical diagnosis and biomedical research. The discovery of
extracellular vesicles (EV) in urine opened a new fast‐growing scientific field. In the last …

[HTML][HTML] PDF receptor signaling in Drosophila contributes to both circadian and geotactic behaviors

I Mertens, A Vandingenen, EC Johnson, OT Shafer… - Neuron, 2005 - cell.com
Summary The neuropeptide Pigment-Dispersing Factor (PDF) is a principle transmitter
regulating circadian locomotor rhythms in Drosophila. We have identified a Class II (secretin …

PPARα gene expression correlates with severity and histological treatment response in patients with non-alcoholic steatohepatitis

…, P Lefebvre, MR Taskinen, W Van Hul, I Mertens… - Journal of …, 2015 - Elsevier
Background & Aims Peroxisome proliferator-activated receptors (PPARs) have been
implicated in non-alcoholic steatohepatitis (NASH) pathogenesis, mainly based on animal …

Gaze motor asymmetries in the perception of faces during a memory task

I Mertens, H Siegmund, OJ Grüsser - Neuropsychologia, 1993 - Elsevier
In 33 male and female adult volunteers, eye position recording were performed by means of
an infrared reflection technique. Slides of randomly shuffled black-and-white photographs …

The senile lung: comparison with normal and emphysematous lungs 1. Structural aspects

EK Verbeken, M Cauberghs, I Mertens, J Clement… - Chest, 1992 - Elsevier
As part of a study of the structural-functional correlations of excised human lungs obtained at
autopsy, the parenchyma and peripheral airways were examined by means of morphometric …

Obesity and persistent organic pollutants: possible obesogenic effect of organochlorine pesticides and polychlorinated biphenyls

…, A Covaci, T Geens, L Roosens, H Neels, I Mertens… - …, 2011 - Wiley Online Library
Persistent organic pollutants (POPs) are endocrine‐disrupting chemicals associated with the
development of the metabolic syndrome and type 2 diabetes. In humans, little is known …