Opioid-free anesthesia (OFA) is emerging as a new stimulating research perspective. The
rationale to propose OFA is based on the aim to avoid the negative impact of intraoperative …

BACKGROUND Complex spinal procedures are associated with intense pain in the
postoperative period. Adequate peri-operative pain management has been shown to …

The health sector is a major contributor to climate change through its large carbon footprint.
Hospitals are highly energy and resource intensive. Operating rooms (ORs) contribute to a …

Importance Fluid therapy is an important component of care for patients with traumatic brain
injury, but whether it modulates clinical outcomes remains unclear. Objective To determine …

Importance It is not known if use of colloid solutions containing hydroxyethyl starch (HES) to
correct for intravascular deficits in high-risk surgical patients is either effective or safe …

Introduction This study aimed to evaluate the pupillary dilatation reflex (PDR) during a
tetanic stimulation to predict insufficient analgesia before nociceptive stimulation in the …

Abstract The French Society of Anaesthesia and Intensive Care Medicine (SFAR) published
experts' guidelines on the care of postoperative pain. This was an update of the 2008 …

Background The analgesic efficacy of ketoprofen has been shown after moderate-and
severe-pain surgery, and the analgesic efficacy of nefopam has been shown after moderate …

BACKGROUND: Hepatocellular carcinoma (HCC) is an aggressive cancer with limited
therapeutic options. Retrospective studies have shown that the administration of local …

Background and objectives Effective pain control improves postoperative rehabilitation and
enhances recovery. The aim of this review was to evaluate the available evidence and to …