In a double-blinded, randomized, prospective multi-center study of 695 women, we
investigated whether epidural injection of sufentanil added to 0.125% bupivacaine with …

Although opioids provide effective analgesia, largely unsubstantiated concerns about opioid-
induced tolerance, physical dependence and addiction have limited their appropriate use …

The absorption and sedation following an intranasal dose of sufentanil were evaluated and
compared with those of the same dose given intravenously. Sixteen adult patients …

In contrast to other opioids, fentanyl and buprenorphine share a number of physicochemical
properties that render both agents potentially suitable for transdermal delivery. However …

Sufentanil, a short‐acting and potent narcotic agent, was studied as a premedicant
administered by the nasal route. A total dose of 5 μg appeared to be too low, while either 10 …

Maternal and umbilical venous plasma was obtained at delivery from 8 mothers and their
neonates after an iv bolus injection of alfentanil, and from 6 mothers and their neonates after …

Alfentanil disposition after an intravenous bolus of 50 µg/kg was followed in 15 elderly
surgical patients and was compared to that in nine young adults. A two‐compartment open …

This open‐label, parallel study of 28 men was conducted to evaluate the pharmacokinetics
and safety of fentanyl delivered by the E‐TRANS (fentanyl) electrotransport transdermal …

The combination of sufentanil with bupivacaine plus adrenaline given extradurally for pain
relief during labour was studied in a double-blind trial. One hundred and twenty patients …

An open pilot study was undertaken to evaluate the analgesic properties of epidurally
administered sufentanil in the early postoperative period. After orthopaedic surgery of the …