[HTML][HTML] Interpreting the clinical importance of treatment outcomes in chronic pain clinical trials: IMMPACT recommendations

…, R Dionne, S Hertz, AR Jadad, NP Katz, H Kehlet… - The journal of pain, 2008 - Elsevier
A consensus meeting was convened by the Initiative on Methods, Measurement, and Pain
Assessment in Clinical Trials (IMMPACT) to provide recommendations for interpreting …

Reduction of postoperative mortality and morbidity with epidural or spinal anaesthesia: results from overview of randomised trials

A Rodgers, N Walker, S Schug, A McKee, H Kehlet… - Bmj, 2000 - bmj.com
Objectives: To obtain reliable estimates of the effects of neuraxial blockade with epidural or
spinal anaesthesia on postoperative morbidity and mortality. Design: Systematic review of …

Enhanced recovery after surgery: a consensus review of clinical care for patients undergoing colonic resection

…, J Nygren, J Hausel, M Soop, J Andersen, H Kehlet - Clinical nutrition, 2005 - Elsevier
BACKGROUND & AIMS: Clinical care of patients undergoing colonic surgery differs
between hospitals and countries. In addition, there is considerable variation in rates of …

Persistent postsurgical pain: risk factors and prevention

H Kehlet, TS Jensen, CJ Woolf - The lancet, 2006 - thelancet.com
Acute postoperative pain is followed by persistent pain in 10–50% of individuals after
common operations, such as groin hernia repair, breast and thoracic surgery, leg …

Multimodal approach to control postoperative pathophysiology and rehabilitation

H Kehlet - British journal of anaesthesia, 1997 - Elsevier
Major surgery is still associated with undesirable sequelae such as pain, cardiopulmonary,
infective and thromboembolic complications, cerebral dysfunction, nausea and …

Multimodal strategies to improve surgical outcome

H Kehlet, DW Wilmore - The American journal of surgery, 2002 - Elsevier
Objective: To evaluate the effect of modifying perioperative care in noncardiac surgical
patients on morbidity, mortality, and other outcome measures. Background: New …

Evidence-based surgical care and the evolution of fast-track surgery

H Kehlet, DW Wilmore - Annals of surgery, 2008 - journals.lww.com
Background: Optimization of postoperative outcome requires the application of evidence-
based principles of care carefully integrated into a multimodal rehabilitation program …

The value of “multimodal” or “balanced analgesia” in postoperative pain treatment

H Kehlet, JB Dahl - Anesthesia & Analgesia, 1993 - journals.lww.com
Background Figure 1 shows the pathways of nociceptive stimuli, including those conducting
pain, from the site of surgical injury passing through the peripheral nervous system to the …

Anaesthesia, surgery, and challenges in postoperative recovery

H Kehlet, JB Dahl - The Lancet, 2003 - thelancet.com
Surgical injury can be followed by pain, nausea, vomiting and ileus, stress-induced
catabolism, impaired pulmonary function, increased cardiac demands, and risk of …

Chronic pain as an outcome of surgery: a review of predictive factors

FM Perkins, H Kehlet - The Journal of the American Society of …, 2000 - pubs.asahq.org
Methods We performed a computerized search of the medical literature using the OVID
search engine (OVID Technologies, Wolters Kluwer, Amsterdam, The Netherlands). The …