Evidence-based medicine depends on the existence of controlled clinical trials that establish
the safety and efficacy of specific therapeutic techniques. Many interventions in clinical …

Consensus guidelines developed by an expert panel are helpful to clinicians when there is
variation in practice and lack of a firm evidence base for an intervention, such as intraspinal …

Background and Objectives: Radiofrequency (RF) denervation of the sacroiliac (SI) joint has
been advocated for the treatment of sacroiliac syndrome, yet no clinical studies or case …

Acute and chronic pain are different clinical entities. Acute pain is provoked by a specific
disease or injury, serves a useful biologic purpose, is associated with skeletal muscle spasm …

Background In 2006, the authors observed a cluster of three deaths, which circumstances
suggested were opioid-related, within 1 day after placement of intrathecal opioid pumps for …

This study was performed in order to determine concentration-effect, and graded and
quantal dose-response relationships for the clinical administration of intravenous (IV) …

Background Traditional strategies for myofascial pain relief provide transient, incomplete,
variable, or unpredictable outcomes. Botulinum toxin is itself an analgesic but can also …

Despite intravenous patient-controlled analgesia's (IV-PCA) increasing popularity, the
psychological and pharmacological factors upon which patient satisfaction with IV-PCA are …

Opioids forM the cornerstone of the pharmacologic armamentarium for the treatment of pain.
Despite their long history of use, much confusion and misperception still surrounds their use …

A retrospective analysis was done on 100 patients who had received cervical epidural
steroid injections for neck pain and cervical radiculopathy to identify the predictors of …