BACKGROUND: Thoracotomy induces severe postoperative pain and impairment of
pulmonary function, and therefore regional analgesia has been intensively studied in this …

Summary The PROSPECT Working Group, a collaboration of anaesthetists and surgeons,
conducts systematic reviews of postoperative pain management for different surgical …

Existing general guidelines for perioperative pain management do not consider procedure-
specific differences in analgesic efficacy or applicability of a given analgesic technique. For …

The haemodynamic effects of propofol, given as a single dose of 2 mg kg− 1 immediately
followed by a continuous infusion of 6 mg kg− 1 h− 1, were studied in 10 elderly patients …

The disposition of the intravenous anesthetic propofol was studied when administered as a
constant rate infusion at 3, 6, and 9 mg [middle dot] kg1 [middle dot] hr-1 for at least 2 hr to …

Background. Ketorolac is approved for the relief of postoperative pain but concerns have
been raised over a possible risk of serious adverse effects and death. Two regulatory …

We have investigated the effect of treatment with tranexamic acid, an inhibitor of fibrinolysis,
on blood loss, blood transfusion requirements and blood coagulation in a randomized …

Background The pharmacokinetic profiles of sufentanil available in the literature are
conflicting because of methodologic differences. Length of sampling and assay sensitivity …

The hypnotic agent propofol has pharmacokinetic characteristics that allow for rapid onset
and offset of drug effect and fast elimination from the body. Elderly patients show a greater …

The reported incidence of emetic symptoms in surgical patients varies from 8-92%.
Intractable postoperative nausea and vomiting remains one of the most unpleasant side …