Leptin and the hypothalamo-pituitary–adrenal stress axis

EW Roubos, M Dahmen, T Kozicz, L Xu - General and comparative …, 2012 - Elsevier
Leptin is a 16-kDa protein mainly produced and secreted by white adipose tissue and
informing various brain centers via leptin receptor long and short forms about the amount of …

TRH acts as a multifunctional hypophysiotropic factor in vertebrates

L Galas, E Raoult, MC Tonon, R Okada… - General and …, 2009 - Elsevier
Thyrotropin-releasing hormone (TRH) is the first hypothalamic hypophysiotropic
neuropeptide whose sequence has been chemically characterized. The primary structure of …

From frog integument to human skin: dermatological perspectives from frog skin biology

IS Haslam, EW Roubos, ML Mangoni… - Biological …, 2014 - Wiley Online Library
For over a century, frogs have been studied across various scientific fields, including
physiology, embryology, neuroscience,(neuro) endocrinology, ecology, genetics …

[HTML][HTML] Chronic stress induces sex-specific alterations in methylation and expression of corticotropin-releasing factor gene in the rat

L Sterrenburg, B Gaszner, J Boerrigter, L Santbergen… - PloS one, 2011 - journals.plos.org
Background Although the higher prevalence of depression in women than in men is well
known, the neuronal basis of this sex difference is largely elusive. Methods Male and female …

Sex‐dependent and differential responses to acute restraint stress of corticotropin‐releasing factor–producing neurons in the rat paraventricular nucleus, central …

L Sterrenburg, B Gaszner, J Boerrigter… - Journal of …, 2012 - Wiley Online Library
Male and female rodents respond differently to acute stress. We tested our hypothesis that
this sex difference is based on differences in stress sensitivity of forebrain areas, by …

Sex-specific differences in the dynamics of cocaine-and amphetamine-regulated transcript and nesfatin-1 expressions in the midbrain of depressed suicide victims vs …

B Bloem, L Xu, É Morava, G Faludi, M Palkovits… - …, 2012 - Elsevier
An intriguing novel pathophysiological insight into mood disorders is the notion that one's
metabolic status influences mood. In rodents, cocaine-and amphetamine-regulated …

Restraint stress alters the secretory activity of neurons co-expressing urocortin-1, cocaine-and amphetamine-regulated transcript peptide and nesfatin-1 in the mouse …

B Okere, L Xu, EW Roubos, D Sonetti, T Kozicz - Brain research, 2010 - Elsevier
Central stress regulatory pathways utilize various neuropeptides, such as urocortin-1 (Ucn1)
and cocaine-and amphetamine-regulated transcript peptide (CART). Ucn1 is most …

Monitoring neurotransmitter release using surface-enhanced Raman spectroscopy

RJ Dijkstra, WJJM Scheenen, N Dam… - Journal of neuroscience …, 2007 - Elsevier
Surface-enhanced Raman spectroscopy (SERS) is a promising tool to monitor
neurotransmitter release at the single-cell level: it is a sensitive technique that provides …

The amygdala, a relay station for switching on and off pain

T Rouwette, P Vanelderen, EW Roubos… - … Journal of Pain, 2012 - Wiley Online Library
Neuropathic pain is strongly associated with mood disorders like anxiety and depression.
Corticotropin‐releasing factor (CRF) plays a prominent role in these disorders as it is up …

Overexpression of corticotropin‐releasing hormone in transgenic mice and chronic stress‐like autonomic and physiological alterations

A Dirks, L Groenink, JA Bouwknecht… - European Journal of …, 2002 - Wiley Online Library
To gain a greater insight into the relationship between hyperactivity of the corticotropin‐
releasing hormone (CRH) system and autonomic and physiological changes associated …