Does cryoneurolysis result in persistent motor deficits? A controlled study using a rat peroneal nerve injury model

SB Shah, S Bremner, M Esparza, S Dorn… - Regional Anesthesia & …, 2020 - rapm.bmj.com
Background Cryoneurolysis of peripheral nerves uses localised intense cold to induce a
prolonged block over multiple weeks that has the promise of providing potent analgesia …

mTOR regulates peripheral nerve response to tensile strain

JM Love, BG Bober, E Orozco… - Journal of …, 2017 - journals.physiology.org
While excessive tensile strain can be detrimental to nerve function, strain can be a positive
regulator of neuronal outgrowth. We used an in vivo rat model of sciatic nerve strain to …

[HTML][HTML] Quantitative evaluation of rat sciatic nerve degeneration using high-frequency ultrasound

Y Wu, V Barrere, A Han, MP Andre, E Orozco… - Scientific reports, 2023 - nature.com
In this study, we evaluated the utility of using high-frequency ultrasound to non-invasively
track the degenerative process in a rat model of peripheral nerve injury. Primary analyses …

Rotator cuff muscle fibrosis can be assessed using ultrashort echo time magnetization transfer MRI with fat suppression

EY Chang, A Suprana, Q Tang, X Cheng… - NMR in …, 2024 - Wiley Online Library
Muscle degeneration following rotator cuff tendon tearing is characterized by fatty infiltration
and fibrosis. While tools exist for the characterization of fat, the ability to noninvasively …

[HTML][HTML] Injured nerves respond favorably to an integrated tension-and conduit-based regenerative strategy

TH Chuang, E Orozco, JJ Nam, K Vaz… - Frontiers in …, 2023 - frontiersin.org
Numerous synthetic, hybrid, and biological grafts and conduits have been deployed to
facilitate axonal regeneration across peripheral nerve gaps. Though some strategies have …

[HTML][HTML] A comparative assessment of lengthening followed by end-to-end repair and isograft repair of chronically injured peripheral nerves

HM Howarth, E Orozco, RM Lovering, SB Shah - Experimental neurology, 2020 - Elsevier
In order to repair chronic nerve injuries (injuries repaired after a long delay), the damaged
nerve segments are resected and stumps are bridged by grafts. Autografts remain the gold …

Decoupled epineurial and axonal deformation in mouse median and ulnar nerves

J Sung, J Sikora‐Klak, SY Adachi, E Orozco… - Muscle & …, 2019 - Wiley Online Library
Introduction Peripheral nerves accommodate mechanical loads during joint movement.
Hypothesized protective features include increased nerve compliance near joints and …

[HTML][HTML] A guide to reducing adverse outcomes in rabbit models of sciatic nerve injury

E Orozco, K Masuda, SB Shah - Laboratory animal research, 2021 - Springer
Background Peripheral nerve damage can have debilitating consequences. Rabbit sciatic
nerve transection models allow the effective evaluation of surgical repair strategies for large …

[HTML][HTML] Rumination syndrome: diagnostic and therapeutic difficulties of a not so uncommon disorder

AG Casado, MJL Liñán, EB Orozco… - Anales de Pediatría …, 2018 - Elsevier
Introduction Rumination syndrome is an uncommon gastrointestinal functional disorder that
may be difficult to diagnose, as not many physicians are aware of this condition. In many …

P56. A combination of human chondrocytes and transduced cells expressing TGF-ß1 improves the structural recovery of degenerated discs in rabbit anular puncture …

K Masuda, K Red, Y Ge, E Orozco, M Brown… - The Spine Journal, 2023 - Elsevier
BACKGROUND CONTEXT Cells in degenerated discs show a decrease in cell number with
the low synthetic activity of matrix molecules. The injection of various growth factors, such as …