Nicotinic acetylcholine receptors are members of the ligand-gated ion channel superfamily,
that includes also gamma-amino-butiric-acidA, glycine, and 5-hydroxytryptamine3 receptors …

The bispectral index (BIS) and a sedation score were used to determine and compare the
effect of propofol in the presence of fentanyl, alfentanil, remifentanil and sufentanil. Seventy …

We have investigated the interaction between magnesium sulphate 40 mg kg− 1 iv and
vecuronium. First, we determined the effect of pretreatment with magnesium on the potency …

Background Recent laboratory studies showed that exposure to supraclinical concentrations
of propofol can induce cell death of immature neurons. However, no data are available …

Ketamine, a noncompetitive antagonist of the N-methyl-d-aspartate type of glutamate
receptors, was reported to induce neuronal cell death when administered to produce …

Background Altered central nervous system sensory processing (neuroplasticity) is a basic
mechanism underlying postoperative pain that can be made visible using quantitative …

Background: Doses of sugammadex required to reverse deep, moderate, and shallow
rocuronium-induced neuromuscular blockade have been established. However, no …

Increased or decreased gain in central nervous system processing after surgery, ie
neuroplasticity, may play an important role in postoperative pain. Identification of patient …

We have investigated the potential of rocuronium 0.6 mg kg-1 (2xED95) and 0.9 mg kg-1
(3xED95) for rapid sequence induction in 100 children, aged 3-7 yr. Intubating conditions …

Magnesium sulphate (MgSO4) is currently used for haemodynamic control during
anaesthesia and the early postoperative period. We have investigated the effect of this …