Drug‐induced liver injury (DILI) is the most frequent reason cited for the withdrawal of
approved drugs from the market and accounts for up to 15% of the cases of acute liver …

One third of the global population has been acutely infected with hepatitis B virus (HBV);
less than 1% of patients with acute infection will develop fulminant hepatitis. 1 Approximately …

Background The reported prevalence of chronic pain after spinal cord injury (SCI) varies
widely due, in part, to differences in the taxonomy of chronic pain. A widely used …

YMDD variants of hepatitis B virus (HBV) emerge in some patients with chronic hepatitis B
who receive lamivudine. YMDD variants were examined in 794 patients in 4 controlled …

Many pharmacokinetic investigations in the elderly population reveal decreased clearance
of lipophilic drugs metabolized by the cytochrome P450 enzymes; however, few studies …

Background: Challenges exist in the clinical diagnosis of drug-induced liver injury (DILI) and
in obtaining information on hepatotoxicity in humans. Objective:(i) To develop a unified list …

Hepatic iron concentration has consistently been observed as being directly correlated with
the response to interferon therapy in chronic hepatitis C virus (HCV). We therefore …

Importance Coronavirus disease 2019 (COVID-19) confers significant risk of acute kidney
injury (AKI). Patients with COVID-19 with AKI have high mortality rates. Objective Individuals …

Objective: Irritable bowel syndrome (IBS) is diagnosed by the presence of a constellation of
symptoms fulfilling the Manning or Rome Criteria, after exclusion of organic disease. To …

Spinal cord injury (SCI) is a devastating condition with limited pharmacological treatment
options to restore function. Regenerative approaches have recently attracted interest as an …