User profiles for "author:Bin Zheng"

Bin Zheng

- Verified email at ou.edu - Cited by 13139

Bin Zheng

- Verified email at cshs.org - Cited by 8379

The regulator of G protein signaling family

L De Vries, B Zheng, T Fischer, E Elenko… - Annual review of …, 2000 - annualreviews.org
Regulator of G protein signaling (RGS) proteins are responsible for the rapid turnoff of G
protein–coupled receptor signaling pathways. The major mechanism whereby RGS proteins …

Recent advances and clinical applications of deep learning in medical image analysis

X Chen, X Wang, K Zhang, KM Fung, TC Thai… - Medical Image …, 2022 - Elsevier
Deep learning has received extensive research interest in developing new medical image
processing algorithms, and deep learning based models have been remarkably successful …

Malaria in the Greater Mekong Subregion: heterogeneity and complexity

L Cui, G Yan, J Sattabongkot, Y Cao, B Chen, X Chen… - Acta tropica, 2012 - Elsevier
The Greater Mekong Subregion (GMS), comprised of six countries including Cambodia,
China's Yunnan Province, Lao PDR, Myanmar (Burma), Thailand and Vietnam, is one of the …

[PDF][PDF] AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant mice

YU Li, S Xu, MM Mihaylova, B Zheng, X Hou, B Jiang… - Cell metabolism, 2011 - cell.com
AMPK has emerged as a critical mechanism for salutary effects of polyphenols on lipid
metabolic disorders in type 1 and type 2 diabetes. Here we demonstrate that AMPK interacts …

[HTML][HTML] Activation of caspase-3 is an initial step triggering accelerated muscle proteolysis in catabolic conditions

J Du, X Wang, C Miereles, JL Bailey… - The Journal of …, 2004 - Am Soc Clin Investig
With trauma, sepsis, cancer, or uremia, animals or patients experience accelerated
degradation of muscle protein in the ATP-ubiquitin-proteasome (Ub-P'some) system. The …

PGC-1α, A Potential Therapeutic Target for Early Intervention in Parkinson's Disease

B Zheng, Z Liao, JJ Locascio, KA Lesniak… - Science translational …, 2010 - science.org
Parkinson's disease affects 5 million people worldwide, but the molecular mechanisms
underlying its pathogenesis are still unclear. Here, we report a genome-wide meta-analysis …

N501Y mutation of spike protein in SARS-CoV-2 strengthens its binding to receptor ACE2

F Tian, B Tong, L Sun, S Shi, B Zheng, Z Wang, X Dong… - elife, 2021 - elifesciences.org
SARS-CoV-2 has been spreading around the world for the past year. Recently, several
variants such as B. 1.1. 7 (alpha), B. 1.351 (beta), and P. 1 (gamma), which share a key …

Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease

MM Lipinski, B Zheng, T Lu, Z Yan… - Proceedings of the …, 2010 - National Acad Sciences
Dysregulation of autophagy, a cellular catabolic mechanism essential for degradation of
misfolded proteins, has been implicated in multiple neurodegenerative diseases. However …

[PDF][PDF] AMPK-dependent degradation of TXNIP upon energy stress leads to enhanced glucose uptake via GLUT1

N Wu, B Zheng, A Shaywitz, Y Dagon, C Tower… - Molecular cell, 2013 - cell.com
Thioredoxin-interacting protein (TXNIP) is an α-arrestin family protein that is induced in
response to glucose elevation. It has been shown to provide a negative feedback loop to …

Improving the performance of CNN to predict the likelihood of COVID-19 using chest X-ray images with preprocessing algorithms

M Heidari, S Mirniaharikandehei, AZ Khuzani… - International journal of …, 2020 - Elsevier
Objective This study aims to develop and test a new computer-aided diagnosis (CAD)
scheme of chest X-ray images to detect coronavirus (COVID-19) infected pneumonia …