Current factor IX (FIX) products display a half-life (t1/2) of∼ 18 hours, requiring frequent
intravenous infusions for prophylaxis and treatment in patients with hemophilia B. This open …

This randomized, double-blind, crossover study investigated the potential effects of
tolterodine ((R)-N, N-diisopropyl-3-(2-hydroxy-5-methyl-phenyl)-3-phenylpropanamine, CAS …

The effects of the anesthetic agents propofol and methohexital on seizure duration, clinical
outcome, recovery, and memory in electroconvulsive therapy (ECT) were studied in a …

Anakinra is an effective, well-tolerated, long-term anti-inflammatory treatment for cryopyrin-
associated periodic syndromes (CAPS), yet evidence shows that it can induce the …

Background Postdural puncture headache (PDPH) and backache are well known
complications of spinal anaesthesia. The incidence of PDPH may be significant in young …

A bioequivalence study with terodiline (Mictrol®) was performed in 8 healthy volunteers
given a 25 mg oral dose of either of two solid dosage forms together with a water solution of …

To improve routines in clinical practice and research, it is important that new tests are
thoroughly evaluated before they gain widespread application. This includes establishing …

The plasma fluoride and bromide concentrations were studied in operating theatre
personnel. When enflurane was used, the increase in plasma fluoride concentration could …

As a target group, geriataric patients were selected for pharmacokinetic studies with
terodiline (Mictrol), an anticholinergic and calcium antagonist drug effective in the treatment …

Nitrous oxide is used in dentistry for sedation and analgesia. Chronic occupational exposure
of dental personnel to trace concentration of nitrous oxide has been reported as a potential …