Table 4

Rate of infectious complications after lower extremity perineural catheters

Study (year)Incidence of infectionComments
Neuburger et al (2007)307 2285 perineural catheters (upper or lower limb).
Incidence of infection: femoral catheter (3.3%), posterior popliteal (2.8%).
Duration of catheter placement constitutes a risk factor.
Cuvillon et al (2001)308 211 femoral catheters.
Colonization with bacteremia in 3 (15%) patients. Bacterial colonization occurred in 57% of catheters at 48 hours, primarily S taphylococcus (71%) and E nterococcus (10%).
Catheters removed at 48 hours and cultures done, patients followed for 48 hours and 6 weeks.
Borgeat et al (2006)309 1001 popliteal sciatic catheters.
0% incidence of infection
Patients followed for 12 weeks.
Compere et al (2009)283 400 popliteal sciatic catheters.
1 (0.25%) case of infection.
One case of thigh abscess with methicillin-resistant S taphylococcus aureus.
Capdevila et al (2005)286 1416 patients with upper or lower limb perineural catheters.
1/683 (0.07%) abscess occurred after a femoral catheter in a diabetic woman
No infection occurred after fascia iliaca (94), sciatic (32), popliteal (167), or distal (38) catheter infusions—median duration of 56 hours.
Rates of positive bacterial colonization of catheters, upper and lower extremity: 29% (278/969).
Risk factors for local inflammation/infection include intensive care confinement, catheter duration greater than 48 hours, male gender, absence of antibiotic prophylaxis.
Wiegel et al (2007)310 1398 perineural catheters (upper or lower limb).
Local inflammation: 4/628 (0.6%) femoral catheters; 4/549 (0.7%) sciatic catheters.
Local infection: 3/628 (0.5%) femoral catheters; 0% sciatic catheters.
2/3 cultures positive: 1—S taphylococcus epidermidis; 1—S taphylococcus aureus; no patient showed signs of systemic infection.
Aveline et al (2011)306 760 perineural catheters (upper or lower limb).
Incidence of colonization: 42/465 (9%) femoral catheters; 3/42 (7.1%) subgluteal catheters; 6/63 (9.5%) popliteal catheters.
No patient showed local or systemic inflammation at the time of catheter removal.
Schroeder et al (2012)311 Femoral catheters.
Incidence of colonization: 3/48 (6.3%) in BIOPATCH (chlorhexidine-impregnated patch) patients compared with 2/47 (4.3%) non-BIOPATCH patients (p>0.999).
Femoral catheters inserted and tunneled following chlorhexidine cleansing.