Patients with history of hypersensitivity reaction to iodinated contrast medium and given contrast for their interventional pain procedures
| Patient details | Prior reactions | Year | Procedure | Contrast (mg) | Reaction | Other comments |
| 67, F | Patient has history of throat swelling when given contrast. Name of contrast or procedure not stated. | 2007 | Right L5 TF-ESI | Iopamidol, 2 mL (700 mg) | None | History of allergy to shellfish. Prednisone 50 mg 13 hours and diphenhydramine 1 hour before procedure |
| 2007 | Right L5 TF-ESI | Iopamidol, 2 mL (700 mg) | None | Same premedication as above. | ||
| 2013 | Right L5 TF-ESI | Gadopentetate, 2 mL (1 mmol) | None | No allergy protocol. | ||
| 2013 | Right L5–S1 IL ESI | Gadopentetate, 2 mL (1 mmol) | None | No allergy protocol. | ||
| 2013 | Right L5 TF-ESI | Iohexol 3 mL (1050 mg) | None | No allergy protocol. Patient contacted later, advised to take prednisone 50 mg immediately and 25 mg at night and in the morning and diphenhydramine for 2 days. | ||
| 87, F | Patient stated that she was allergic to contrast given for a previous angiogram, specific reaction not stated. | 2010 | Right L4 TF-ESI | Iopamidol, 2 mL (700 mg) | None | History of allergy to iodine. |
| 2015 | L5–S1 IL ESI | Iohexol 3 mL (1050 mg) | None | Patient contacted 45 min later, took 25 mg diphenhydramine. No symptoms 6 hours after procedure. | ||
| 2015 | Right L5 TF ESI | Gadopentetate, 3 mL (1.5 mmol) | None | No allergy protocol. | ||
| 47, M | Hives from ESI, iohexol | 2012 | Right L4 TF ESI | Iohexol 2 mL (700 mg) | None | No allergy protocol. |
| 2012 | Right L5 TF ESI | Iohexol 2 mL (700 mg) | None | No allergy protocol. | ||
| 2014 | Right L5 TF ESI | Iohexol 3 mL (1050 mg) | Hives in upper back, face, legs | Patient given diphenhydramine 50 mg and dexamethasone 4 mg. Had skin testing (see text). | ||
| 2014 | Right SI joint injection | Iohexol 3 mL (1050 mg) | None | Prednisone with prednisone 50 mg 13 hours, 7 hours, and 1 hour before and diphenhydramine 100 mg 1 hour prior to injection. | ||
| 2014 | Right L4 TF-ESI | Iohexol 1 mL (350 mg) | Hives on forehead, neck and arms | Same allergy protocol as above. | ||
| 2014 | Right SI joint injection | Gadopentetate, 2 mL (1 mmol) | Minimal hives on neck | No allergy protocol. | ||
| 50, F | Patient with history of allergy to contrast; procedure, name, and amount of contrast not noted. | 2015 | L5–S1 IL ESI | Iohexol 3 mL (1050 mg) | None | Physician unaware that iohexol was unintentionally given, patient not followed up. |
| 2016 | L5–S1 IL ESI | Iohexol 3 mL (1050 mg) | None | Iohexol injection recognized, patient watched for 30 min. | ||
| 2016 | C7–T1 IL ESI | Gadopentetate, 3 mL (1.5 mmol) | None | |||
| 89, F | Urticaria and pruritus from IVP (2002), 100 mL injected. Name of contrast not noted in radiology notes. Patient discharged after 1 hour. | 2016 | L5–S1 IL ESI | Iopamidol, 1 mL (350 mg) | None | History of allergy to iodine. |
| 2016 | L5–S1 IL ESI | Gadopentetate, 2 mL (1 mmol) | None | No allergy protocol. | ||
| 2016 | L5–S1 IL ESI | Gadopentetate, 2 mL (1 mmol) | None | No allergy protocol. | ||
| 60, F | Severe angioedema and throat swelling from contrast. | 2016 | L5–S1 IL ESI | Iohexol, 3 mL (1050 mg) | None | No allergy protocol. Physician not aware iohexol was given. |
| 2017 | L5–S1 IL ESI | Gadopentetate, 2 mL (1 mmol) | None | Unintentional iohexol injection in 2016 noted, gadopentetate used. |
Both iopamidol and iohexol are low osmolar contrast media and have iodine concentrations of 350 mg/mL.9
Gadopentetate dimeglumine is gadolinium-based contrast agent with a concentration of 0.5 mmol/mL.24
ESI, Epidural steroid injection; IL, Interlaminar; IVP, Intravenous pyelogram; SIJ, Sacroiliac joint; TF, Transforaminal.