Table 1

Bolus dosing characteristics

BupivacaineRopivacaine
AllPVBTAPAllPVBTAP
Bolus dosing
 Concentration (%)0.25 (0.125–0.5) n=27240.27 (0.125–0.5) N=22500.25 (0.125–0.375) N=4740.5 (0.2–0.75), n=29780.5 (0.2–0.75), n=25180.5 (0.1–1.0), n=460
 Volume (mL)20 (6.5–60) N=223620 (8–60) N=197230 (5–40) N=26420 (10–60), n=258120 (10–50), n=214030 (17.5–100), n=441
 Weight-based volume (mL/kg)0.4 (0.1–1.6) N=4880.3 (0.1–0.4) N=2780.4 (0.4–0.8) N=2100.3 (0.1–0.4), n=3970.3 (0.1–0.4), n=3780.4 (0.4–0.4), n=19
Overall bolus dosing (calculated)
 Median dose (mg/kg)1.0 (0.18–2.1) N=27241.0 (0.23–2.1) N=22501.0 (0.14–2.0) N=4741.4 (0.4–3.0), n=29781.3 (0.43–2.5), n=25182.1 (0.6–4.3), n=460
 IQR (mg/kg)0.7–1.40.7–1.40.8–1.40.8–2.10.8–2.11.0–2.9
 90th percentile dose (mg/kg)1.751.72.02.42.13.0
 Mean±SD (mg/kg)1.1±0.51.1±0.51.1±0.51.5±0.761.4±0.72.0±1.0
  • Unless otherwise specified, data presented as median (95% CI), n.

  • PVB, paravertebral; TAP, transversus abdominis plane.