PGIC descriptor PGIC score | Worsening | None | Small | Medium | Large |
1–3 | 4 | 5 | 6 | 7 | |
(n=7) | (n=72) | (n=9) | (n=10) | (n=37) | |
Phantom limb pain score improvement (Numeric Rating Scale) | |||||
Mean (SD) | −0.6 (2.1) | −0.1 (1.0) | 0.9 (1.9) | 3.0 (1.8) | 5.0 (2.0) |
Mean (95% CI) | −0.6 (−1.3, 3) | −0.1 (−0.3, 0.2) | 0.9 (−0.5, 2) | 3 (2, 5) | 5 (4, 6) |
Median (IQR) | −1 (−0.3, −1.8) | 0 (−0.5, 0) | 2 (0, 2) | 3 (2, 5) | 5 (3, 7) |
Brief Pain Inventory Improvement (Interference Subscale) | |||||
Mean (SD) | 2 (9) | 1.6 (8) | 11 (12) | 22 (16) | 34 (23) |
Mean (95% CI) | 2 (−6, 11) | 1.6 (−0.3, 4) | 11 (1.8, 20) | 22 (10, 34) | 34 (26, 41) |
Median (IQR) | −2 (−4, 8) | 0 (−1, 1) | 8 (1, 18) | 22 (14, 31) | 39 (26, 47) |
n=6 missing outcome at 1 month, replaced using the last observation carried forward method for active (n=3) and placebo (n=3) groups.
Nine patients did not have a PGIC response and were excluded (n=135).