Gadolinium based contrast agents
| Gadolinium-based contrast agent | Type, stability* | Concentration mmol/mL | Usual MRI dose mmol/kg (mL dose in 70 kg person)‡ |
| Gadodiamide (OmniscanR) | Nonionic linear, Low | 0.5 | 0.1 (14 mL) |
| Gadoversetamide (OptimarkR) | Nonionic linear, Low | 0.5 | 0.1 (14 mL) |
| Gadobenate dimeglumine (MultiHanceR)† | Ionic linear, Intermediate | 0.5 | 0.1 (14 mL) |
| Gadopentetate dimeglumine (MagnevistR) | Ionic linear, Intermediate | 0.5 | 0.1 (14 mL) |
| Gadofesveset trisodium (AblavarR, VasovistR) | Ionic linear, Intermediate | 0.25 | 0.03 (8.4 mL) |
| Gadoxetate disodium (EovistR, PrimovistR)† | Ionic linear, Intermediate | 0.25 | 0.025 (7 mL) |
| Gadoteridol (ProHanceR) | Nonionic macrocyclic, High | 0.5 | 0.1 (14 mL) |
| Gadobutrol (GadavistR) | Nonionic macrocyclic, High | 1 | 0.1 (7 mL) |
| Gadoterate meglumine (DotaremR) | Ionic macrocyclic, High | 0.5 | 0.1 (14 mL) |
Adapted from Benzon et al11 (with permission).
*Adapted from Kanda et al.40
†Used for liver MRI.
‡Usual radiology doses for MRI of the brain or body parts.
§0.27 mmol/kg is the lowest doses noted with gadolinium deposition in the brain of patients with chronic renal failure.