Table 3

Changes in pain from baseline to discharge based on receipt of various intravenous migraine medications

MedicationReceived drug, median pain (IQR)*Did not receive drug, median pain (IQR)*P value
Ketorolac−4.5 (−3 to –6.5)
N=513
−6.0 (−3.1 to –7.0)
N=96
0.03
Dihydroergotamine−4.8 (−3.0 to –6.9)
N=556
−5.0 (−3.0 to –7.0)
N=53
0.48
Methylprednisolone−4.0 (−2.0 to –6.5)
N=328
−5.0 (−3.5 to –7.0)
N=281
<0.001
Magnesium−5.0 (−3.0 to –7.0)
N=596
−5.0 (−2.3 to –8.0)
N=13
0.57
Neuroleptics†−5.0 (−3.0 to –7.0)
N=585
−4.0 (−2.3 to –6.4)
N=24
0.37
  • *Pain was assessed on a 0–10 Numerical Rating Scale where 0=no pain and 10=worst pain imaginable.

  • †Neuroleptics included promethazine, prochlorperazine, chlorpromazine, haloperidol, and metoclopramide.