Table 3

Opioid consumption-related outcomes and opioid-related side effects presented as mean±SD, absolute number (proportions) as appropriate, and risk difference (95% CI) between the groups

Placebo groupPENG groupMean difference (95% CI)P value
Intraoperative MED consumption (mg)83.0±29.569.1±25.7−13.8 (0.6 to 27.1)0.04
MED consumption during PACU discharge3.3±8.81.3±3.5−2.0 (−1.2 to 5.3)0.21
MED consumption 48 hours after PACU discharge (mg)14.5±25.018.0±29.23.5 (−16.4 to 9.4)0.59
Postoperative nausea and vomiting
 Nausea5 (13.9%)6 (17.6%)3.8% (−15.6% to 23.3%)0.67
 Vomiting12 (33.3%)4 (11.8%)−21.6% (−0.3% to 41.0%)0.03
  • The mean difference is presented as mean (PENG group) − mean (placebo group) and 95% CI.

  • Intravenous MED (mg) equation: (sufentanil [mcg]) + 11 (remifentanil [mcg] × 0.1) + (tramadol [mg] × 0.1) + (butorphanol [mg] × 5) + 12 (meperidine [mg] × 0.1).

  • MED, morphine equivalent doses; PACU, postanesthesia care unit; PENG, pericapsular nerve group.