Results
| Outcome | Active cryoneurolysis (N=6) | Sham (N=6) |
| Average pain (NRS 0–10) | ||
| POD 1 | 1.5 (1)±1.9 | 4.2 (5.5)±3.4 |
| POD 2 | 1.3 (0)±2.2 | 3.5 (3)±1.2 |
| POD 3 | 1.0 (0)±1.7 | 2.7 (2.5)±1.9 |
| POD 4 | 1.5 (1)±1.6 | 2.4 (2.25)±1.5 |
| POD 7 | 0 (0) | 2.8 (3.5)±1.9 |
| POD 14 | 0 (0) | 1.0 (0)±1.7 |
| POD 21 | 0.7 (0)±1.2 | 1.3 (0)±2.3 |
| Worst pain (NRS 0–10) | ||
| POD 1 | 3.0 (3.5)±2.5 | 6.0 (8)±4.5 |
| POD 2 | 1.8 (0)±3.0 | 6.1 (6.5)±1.9 |
| POD 3 | 2.7 (1)±3.5 | 5.8 (6)±1.7 |
| POD 4 | 3.0 (2)±3.5 | 4.8 (5)±1.8 |
| POD 7 | 0.4 (0)±0.9 | 4.8 (5.5)±3.6 |
| POD 14 | 0.3 (0)±0.5 | 2.7 (0)±4.6 |
| POD 21 | 1.3 (0.5)±2.3 | 2.3 (0)±4.0 |
| Oxycodone (mg) | ||
| POD 1 | 37.1 (27.5)±26.9 | 41.7 (37.5)±31.0 |
| POD 2 | 16.7 (12.5)±15.4 | 35.8 (30)±35.3 |
| POD 3 | 13.3 (2.5)±19.4 | 34.2 (32.5)±25.6 |
| POD 4 | 9.0 (5)±12.4 | 10.8 (12.5)±9.2 |
| POD 7 | 0 (0) | 12.5 (10)±12.6 |
| POD 14 | 0.8 (0)±2.0 | 3.3 (0)±5.7 |
| POD 21 | 0.8 (0)±2.0 | 6.7 (0)±11.5 |
| Sleep disturbance (%) | ||
| POD 1 | 16.7 | 67.7 |
| POD 2 | 16.7 | 50 |
| POD 3 | 16.7 | 16.7 |
| POD 4 | 16.7 | 0 |
| POD 7 | 0 | 0 |
| POD 14 | 0 | 0 |
| POD 21 | 0 | 0 |
NRS, numeric rating scale; POD, postoperative day.