Basivertebral nerve ablation in the former standard care arm: 6-month quality of life results
| Quality of life measurements | Basivertebral nerve ablation in the former standard care arm(n=61) | P-Value |
| Baseline SF-36 (PCS) | ||
| Mean, SD (Range) | 33.1, 5.6 (20.9–45.2) | |
| 3 Month SF-36 (PCS) | n=60* | |
| Mean, SD (Range) | 44.9, 9.1 (23.1–59.7) | |
| Mean Change from Baseline, SD | 11.8, 8.4 | <0.001† |
| 6 Month SF-36 (PCS) | n=58* | |
| Mean, SD (Range) | 45.8, 10.2 (22.3–59.3) | |
| Mean Change from Baseline, SD | 12.6, 9.6 | <0.001† |
| Baseline SF-36 (MCS) | ||
| Mean, SD (Range) | 49.2, 11.6 (21. 6–66.3) | |
| 3 Month SF-36 (MCS) | n=60* | |
| Mean, SD (Range) | 54.5, 8.5 (23.5–66.1) | |
| Mean Change from Baseline, SD | 5.1, 11.1 | <0.001† |
| 6 Month SF-36 (MCS) | n=58* | |
| Mean, SD (Range) | 54.3, 8.5 (23.9–63.6) | |
| Mean Change from Baseline, SD | 5.1, 11.1 | <0.001† |
| Baseline EQ-5D-5L | ||
| Mean, SD (Range) | 0.61, 0.13 (0.28–0.86) | |
| 3 Month EQ-5D-5L | n=60* | |
| Mean, SD (Range) | 0.79, 0.14 (0.43–1.00) | |
| Mean Change from Baseline, SD | 0.18, 0.17 | <0.001† |
| 6 Month EQ-5D-5L | n=58* | |
| Mean, SD (Range) | 0.80, 0.14 (0.48–1.00) | |
| Mean Change from Baseline, SD | 0.20, 0.18 | <0.001† |
Significant differences were observed at 3 and 6 months post basivertebral nerve ablation compared with re-baseline.
*As observed. No imputations for missing values.
†P value from a paired t-test (baseline to 3 and 6 months) for the standard care with BNV ablation group.
EQ-5D-5L, EuroQual Group 5 Dimension 5-Level Quality of Life; MCS, Mental Component Summary; PCS, Physical Component Summary; QOL, quality of life; SF, Short Form.