Composite responder rates (≥15-point ODI and ≥2 cm VAS reduction) | Basivertebral nerve ablation arm (N=66) | Standard care arm (N=74) | P value |
3-Month composite responders, n (%) | n=65* 41 (63.1%) | n=51* 7 (13.7%) | <0.001† |
6-Month composite responders, n (%) | n=60* 35 (58.3%) | n=67‡ 4 (6.0%) | <0.001† |
9-Month composite responders, n (%) | n=60* 37 (61.7%) | 0.07§ | |
12-Month composite responders, n (%) | n=61* 40 (65.6%) | 0.02§ | |
Composite responder rates
(≥15-point ODI and ≥2 cm VAS reduction) |
Basivertebral nerve ablation in the former standard care arm
(n=61) | ||
3-Month composite responders, n (%) | n=60* 34 (56.7%) | 0.30§ | |
6-Month composite responders, n (%) | n=58* 36 (62.1%) | 0.07§ |
Composite responder rates were defined as ≥15-point reduction in Oswestry Disability Index (ODI) and ≥2 cm reduction in Visual Analog Scale (VAS). Significant differences were observed at 3 and 6 months between the arms.
*As observed, with no imputation for missing data.
†P value from Fisher’s exact test.
‡Standard care control arm 6 months as last attended (median follow-up of 176.5 days).
§P value from a binomial test.
ODI, Oswestry Disability Index; VAS, Visual Analog Scale.