Basivertebral nerve ablation arm: 12-month quality of life results
| Quality of life measurements | Basivertebral nerve ablation arm(n=66) | P value |
| Baseline SF-36 (PCS) | ||
| Mean, SD (Range) | 32.1, 6.8 (18.4–46.9) | |
| 9 Month SF-36 (PCS) | n=60* | |
| Mean, SD (Range) | 46.8, 9.5 (25.8–60.8) | |
| Mean Change from Baseline, SD | 14.5, 9.5 | <0.001† |
| 12 Month SF-36 (PCS) | 61* | |
| Mean, SD (Range) | 47.0, 9.9 (25.5–62.2) | |
| Mean Change from Baseline, SD | 14.9, 10.2 | <0.001† |
| Baseline SF-36 (MCS) | ||
| Mean, SD (Range) | 53.4, 9.5 (22.2–69.8) | |
| 9 Month SF-36 (MCS) | n=60* | |
| Mean, SD (Range) | 54.1, 8.6 (21.1–64.8) | |
| Mean Change from Baseline, SD | 0.7, 7.5 | 0.48b |
| 12 Month SF-36 (MCS) | n=61* | |
| Mean, SD (Range) | 54.4, 7.6 (26.6–63.5) | |
| Mean Change from Baseline, SD | 0.8, 8.0 | 0.42† |
| Baseline EQ-5D-5L | ||
| Mean, SD (Range) | 0.61, 0.13 (0.27–0.83) | |
| 9 Month EQ-5D-5L | n=60* | |
| Mean, SD (Range) | 0.81, 0.16 (0.42–1.00) | |
| Mean Change from Baseline, SD | 0.19, 0.18 | <0.001† |
| 12 Month EQ-5D-5L | n=61* | |
| Mean, SD (Range) | 0.81, 0.16 (0.35–1.00) | |
| Mean Change from Baseline, SD | 0.19, 0.19 | <0.001† |
Significant differences were observed for the Physical Component Summary but not the Mental Component Summary in the basivertebral nerve ablation treatment arm at 9 and 12 months post procedure compared with baseline.
*As observed. No imputations for missing values.
†P value from a paired t-test (baseline to 9 and 12 months) for the BNV ablation arm.
EQ-5D-5L, EuroQual Group 5 Dimension 5-Level Quality of Life; MCS, Mental Component Summary; PCS, Physical Component Summary; QOL, quality of life; SF, Short Form.