Table 1

Number, severity,* and route of drug administration errors identified in case reports: drugs with at least two case reports

Event severity scale
LowModerateSevereDeath
Drug nameDrug classEvents (n)Incident(s)
Vincristine†‡Chemotherapy19415
Potassium chloride†N/A651
Bupivacaine§Local anesthetic514
Thiocolchicoside†Muscle relaxant44
Gadolinium¶Contrast agent312
Ropivacaine§Local anesthetic312
Vecuronium†Muscle relaxant312
Paracetamol†Pain reliever211
Tranexamic acid‡Antifibrinolytic211
Oxytocin†N/A22
Ephedrine†Nonselective adrenergic agonist22
Succinylcholine†General anesthetic22
Thiopental†General anesthetic22
  • *Incident severity, as defined by the National Reporting and Learning System,23 is as follows: (Low) An unexpected or unintended incident that required extra observation or minor treatment and caused minimal harm to ≥1 person; (Moderate) Any unexpected or unintended incident that resulted in further treatment, possible surgical intervention, canceling of treatment, or transfer to another area, and which caused short-term harm to ≥1 person; (Severe) Any unexpected or unintended incident that caused permanent or long-term harm to ≥1 person; (Death) Any unexpected or unintended event that caused the death of ≥1 person.

  • †Intravenous to epidural.

  • ‡Intravenous to intrathecal.

  • §Epidural to intravenous.

  • ¶Intravenous to intraventricular/extraventricular.

  • N/A, not applicable.