Table 1

Study characteristics and outcomes of interest assessed in included studies

Author/year	Surgery	N	Groups (n)	Surgical anesthesia	Primary outcome	Rest pain scores		Dynamic pain scores		Opioid consumption		Time to first analgesic request	Assessment of block success	Opioid-related adverse effects	Block-related complications	Patient satisfaction	PACU discharge time	Hospital discharge time	Quality of life outcomes	Functional outcomes	Persistent postsurgical pain
Author/year	Surgery	N	Groups (n)	Surgical anesthesia	Primary outcome	Early	Late	Early	Late	Early	Late	Time to first analgesic request	Assessment of block success	Opioid-related adverse effects	Block-related complications	Patient satisfaction	PACU discharge time	Hospital discharge time	Quality of life outcomes	Functional outcomes	Persistent postsurgical pain
*ESPB vs control*
Gürkan 201856	MRM; lumpectomy; SLNB; ALND	50	1.ESPB (25) 2.Control (25)	General	Opioid consumption	●				●				●
Aksu 201951	MRM; lumpectomy; SLNB; ALND	50	1.ESPB (25) 2.Control (25)	General	Opioid consumption	●				●				●
Arora 201937	MRM; ALND	60	1.ESPB (30) 2.Control (30)	General	Opioid consumption	●				●		●		●	●
Singh 201954	MRM	40	1.ESPB (20) 2.Control (20)	General	Opioid consumption	●				●				●		●
Wang 201910	MRM	150	1.ESPB (50) 2.SAPB (50) 3.Control (50)	General	N/S	●	●	●	●	●	●	●		●				●		●
Divatia 202048 *	MRM; ALND	62	1.ESPB (29) 2.Control (33)	General	Time to analgesic request	●						●		●		●
He 202055	MRM; ALND	40	1.ESPB (20) 2.Control (20)	General	Pain scores	●	●	●	●		●	●			●
Gupta 202049 *	Breast cancer surgery	15	1.ESPB (8) 2.Control (7)	General	N/S	●		●		●				●	●	●
Gürkan 20204	MRM; breast conserving surgery	75	1.ESPB (25) 2.PVB (25) 3.Control (25)	General	Opioid consumption	●				●				●
Marzouk 202050 *	MRM; lumpectomy; ALND	50	1.ESPB (25) 2.Control (25)	General	Opioid consumption	●				●				●	●	●
Seelam 202052	MRM	100	1.ESPB (50) 2.Control (50)	General	Opioid consumption	●				●				●	●
Yao 202053	MRM	82	1.ESPB (41) 2.Control (41)	General	Quality of recovery	●		●		●				●	●		●		●

*Data provided from author on clinical trials registry.
ALND, axillary lymph node dissection; Early, ≤24 hours; ESPB, erector spinae plane block; Late, >24 hours; MRM, modified radical mastectomy; PACU, post-anesthesia care unit; PVB, paravertebral block; SAPB, serratus anterior plane block; SLNB, sentinel lymph node biopsy.