Author/year | Pre-incisional analgesia | Surgical analgesia | Supplemental postoperative analgesia | ESPB | |||||
Block timing | Block technique 1. Unilateral 2. Bilateral 3. LA between rhomboideus major and erector spinae 4. LA below erector spinae and above transverse process | Level of block | Localization | Assessment of block success | ESPB bolus | ||||
Gürkan 201856 | None | Fentanyl 2 mcg/kg IV | Paracetamol 1 g IV; tramadol 100 mg IV; PCA morphine | Preop | 1, 4 | T4 | USG | No | 20 mL 0.25% bupivacaine |
Aksu 201951 | None | Fentanyl 2 mcg/kg IV | Paracetamol 1 g IV; tramadol 100 mg IV; PCA morphine | Preop | 1, 4 | T2 and T4 | USG | No | 20 mL 0.25% bupivacaine |
Arora 201937 | N/S | Fentanyl 0.5 mcg/kg-1 mcg/kg IV | PCA morphine | Preop | 1, 4 | T5 | USG | Yes | 0.4 mL/kg 0.5% ropivacaine |
Singh 201954 | None | Morphine 0.1 mg/kg IV | Diclofenac 1.5 mg/kg IV q8h; morphine 3 mg IV prn | Preop | 1, 4 | T5 | USG | Yes | 20 mL 0.5% bupivacaine |
Wang 201910 | 1 mcg/kg Dexmed | Sufentanil 0.4 mcg/kg IV; remifentanil 3.5 ng/mL to 4.5 ng/mL IV | Flurbiprofen 50 mg PO prn; sufentanil 5 mcg IV prn; PCA sufentanil | Preop | 1, 4 | T4 and T5 | USG | N/S | 20 mL 0.375% ropivacaine |
Divatia 202048 * | N/S | Fentanyl 0.5 mg/kg IV | Paracetamol 15 mg/kg IV q8h; fentanyl IV prn | Intraop | 1,4 | T5 | USG | Yes | 20 mL 0.25% bupivacaine |
Gupta 202049 * | 0.5 mcg/kg/hr Dexmed | Fentanyl 2 mcg/kg (if no block); ketamine 10 mg bolus (if block) | PCA morphine | Preop | 1, 4 | T5 | USG | N/S | 30 mL 0.5% ropivacaine |
Gürkan 20204 | None | Fentanyl 2 mcg/kg IV; tramadol 100 mg IV; paracetamol 1 g IV | Paracetamol 1 g IV q6h; PCA morphine | Preop | 1, 4 | T4 | USG | No | 20 mL 0.25% bupivacaine |
He 202055 | N/S | N/S | Flurbiprofen 50 mg IV prn | Preop | 1,4 | T3 | USG | N/S | 20 mL 0.5% ropivacaine |
Marzouk 202050 * | N/S | N/S | PCA morphine | Preop | 1,4 | T4 or T5 | USG | N/S | 40 mL 0.375% ropivacaine |
Seelam 202052 | None | Fentanyl 0.5 mcg/kg to 1 mcg/kg IV; paracetamol 1 g IV | Paracetamol 1 g IV q8h; morphine 2 mg to 3 mg IV prn | Preop | 1, 4 | T4 | USG | No | 30 mL 0.25% bupivacaine |
Yao 202053 | Flurbiprofen 50 mg IV | Sufentanil 0.5 mcg/kg IV; flurbiprofen 50 mg IV q8h | Flurbiprofen 50 mg q8h; sufentanil 2 mcg IV prn PCA sufentanil | Preop | 1, 4 | T4 | USG | No | 25 mL 0.25% ropivacaine |
*Study from clinical trials registry.
Dexmed, dexmedetomidine; ESPB, erector spinae plane block; h, hour; Intraop, intraoperative; IV, intravenous; LA, local anesthesia; mcg, microgram; min, minute; mL, milliliter; ng, nanogram; N/S, not specified; PCA, patient-controlled analgesia; Preop, preoperative; prn, as needed; q, every; USG, ultrasound guidance.