Patient no. | Number of CFU cultured from | Duration of epidural, hours | |||||||
Extracorporeal segment | Skin swab | Subcutaneous segment | Tip segment | ||||||
EC1 | SkSw1 | SC1 | SC2 | SC3 | T1 | T2 | T3 | ||
2 | 316.5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 173 |
8 | 0 | 16.66 | 0 | 0 | 0 | 0 | 0 | 0 | 76.5 |
11 | 0 | ≥4165 | 0 | 0 | 0 | 0 | 0 | 0 | 73.5 |
12 | 0 | 3332 | 0 | 0 | 0 | 0 | 0 | 0 | 101 |
14 | 1532.7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 69 |
18 | 0 | ≥4165 | 0 | 0 | 0 | 0 | 0 | 0 | 74 |
17 | 0 | 0 | <8.3 | 0 | 0 | 0 | 0 | 0 | 99 |
1 | 0 | ≥4165 | 0 | 0 | <8.3 | 16.7 | 0 | 0 | 77 |
13 | 0 | ≥4165 | 0 | 0 | 0 | 25.0 | 0 | 0 | 80 |
27 | 0 | 0 | 0 | 0 | 0 | 0 | <8.3 | 0 | 73 |
29 | 0 | ≥4165 | 0 | <8.3 | 0 | 0 | 0 | <8.3 | 72 |
7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | <8.3 | 76 |
9 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | <8.3 | 70 |
4 | 0 | 0 | 0 | 0 | 0 | 0 | 41.7 | 0 | 96 |
3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 25.0 | 73 |
5* | ≥4165 | ≥4165 | 1774.3 | 158.3 | 91.6 | Diagnosed as positive and evaluated in clinical lab | 96 |
Values indicate numbers of CFU or in situ duration (hours). No growth is indicated as 0 CFU. Lower detection limit 8.3 CFU. Upper detection limit 4165 CFU. The average duration of epidural therapy in non-colonized patients was 95 hours (range: 72–171 hours) (data not shown).
Many diagnostic microbiology laboratories define at least 100 CFU in quantitativestudies as a threshold indicating colonization.
*Patient with superficial infection.
CFU, colony-forming units; EC1, extracorporeal catheter segment; SC1, subcutaneous catheter segment 1 (superficial); SC2, subcutaneous catheter segment 2; SC3, subcutaneous catheter segment 3 (deep); SkSw1, skin swab; T1, catheter tip segment 1; T2, catheter tip segment 2; T3, catheter tip segment 3 (utmost tip in epidural space).