Table 3

Cox proportional hazard regression analysis to predict chronic postsurgical pain during the first 36 months after thoracic surgery

HR (95% CI)P value*
Age1.01 (1.00 to 1.02)0.23
Sex
 MaleReference
 Female1.20 (1.00 to 1.43)0.04
Preoperative analgesic use1.00 (0.66 to 1.51)0.99
Operative technique
 VATSReference
 Thoracotomy1.02 (0.82 to 1.28)0.84
Operation time, hours1.11 (1.03 to 1.20)<0.01
NRS score at first outpatient visit after surgery1.29 (1.25 to 1.34)<0.001
Postoperative chemotherapy1.55 (1.26 to 1.90)<0.001
Postoperative radiation therapy1.35 (1.05 to 1.74)0.02
Year of surgery
 2007Reference
 20080.77 (0.49 to 1.22)0.27
 20090.65 (0.39 to 1.07)0.09
 20101.05 (0.67 to 1.63)0.84
 20111.29 (0.87 to 1.90)0.20
 20120.92 (0.62 to 1.39)0.70
 20130.98 (0.66 to 1.46)0.92
 20140.88 (0.59 to 1.30)0.51
 20150.94 (0.63 to 1.39)0.76
 20161.14 (0.76 to 1.71)0.52
  • *Tested by Cox proportional hazards regression.

  • NRS, Numeric Rating Scale; VATS, video-assisted thoracic surgery.