RT Journal Article SR Electronic T1 Twelve-month analgesia and rescue, by cooled radiofrequency ablation treatment of osteoarthritic knee pain: results from a prospective, multicenter, randomized, cross-over trial JF Regional Anesthesia & Pain Medicine JO Reg Anesth Pain Med FD BMJ Publishing Group Ltd SP 499 OP 506 DO 10.1136/rapm-2018-100051 VO 44 IS 4 A1 Tim Davis A1 Eric Loudermilk A1 Michael DePalma A1 Corey Hunter A1 David A Lindley A1 Nileshkumar Patel A1 Daniel Choi A1 Marc Soloman A1 Anita Gupta A1 Mehul Desai A1 Elizabeth Cook A1 Leonardo Kapural YR 2019 UL http://rapm.bmj.com/content/44/4/499.abstract AB Background and objectives As a follow-up to the 6-month report,12 this study investigated the analgesic effect of cooled radiofrequency ablation (CRFA) in patients with knee osteoarthritis (OA) 12 months postintervention and its ability to provide pain relief in patients who experienced unsatisfactory effects of intra-articular steroid injection (IAS).Methods Seventy-eight per cent (52/67) of patients originally treated with CRFA were evaluated at 12 months, while at 6 months post-IAS, 82% (58/71) of those patients crossed over to CRFA and assessed 6 months later.Results At 12 months, 65% of the original CRFA group had pain reduction ≥50%, and the mean overall drop was 4.3 points (p<0.0001) on the numeric rating scale. Seventy-five per cent reported ‘improved’ effects. The cross-over group demonstrated improvements in pain and functional capacity (p<0.0001). No unanticipated adverse events occurred.Conclusions This study demonstrates that analgesia following CRFA for OA knee pain could last for at least 12 months and could rescue patients who continue to experience intolerable discomfort following IAS.Clinical trial registration The ClinicalTrials.gov registration number for this study is NCT02343003.