RT Journal Article
SR Electronic
T1 Clinical Comparison of Equipotent Doses of Bupivacaine and Prilocaine in Intravenous Regional Anesthesia
JF Regional Anesthesia: The Journal of Neural Blockade in Obstetrics, Surgery, & Pain Control
JO Reg Anesth Pain Med
FD BMJ Publishing Group Ltd
SP 102
OP 104
DO 10.1136/rapm-00115550-198611020-00013
VO 11
IS 2
A1 A. Lee
A1 D. W. McKeown
A1 J. A. W. Wildsmith
YR 1986
UL http://rapm.bmj.com/content/11/2/102.abstract
AB One hundred patients underwent intravenous regional anesthesia for manipulation of Colles' fracture using prilocaine 0.5% or bupivacaine 0.125% administered in a double-blind manner. Prilocaine produced significantly better analgesia, but was associated with significantly more pain on injection. Minor side effects after tourniquet release were rare. It is apparent that the results of studies on the relative potencies of these agents in animals or human volunteers do not apply to intravenous regional anesthesia when used clinically and that there can be no case for using lower concentrations of bupivacaine to increase its safety.