RT Journal Article
SR Electronic
T1 Epidural Analgesia in a Preeclamptic Parturient After Normalization of a Prolonged Bleeding Time With DDAVP
JF Regional Anesthesia: The Journal of Neural Blockade in Obstetrics, Surgery, & Pain Control
JO Reg Anesth Pain Med
FD BMJ Publishing Group Ltd
SP 448
OP 451
DO 10.1136/rapm-00115550-199520050-00014
VO 20
IS 5
A1 Fragneto, Regina Y.
A1 Datta, Sanjay
YR 1995
UL http://rapm.bmj.com/content/20/5/448.abstract
AB Background and Objectives. Despite several advantages to the use of epidural analgesia for the management of labor pain in preeclamptic parturients, this procedure is withheld from many such patients owing to associated thrombocytopenia and platelet dysfunction.Methods. A preeclamptic parturient with mild thrombocytopenia and platelet dysfunction manifested by a prolonged bleeding time received intravenous DDAVP (0.3 μg/kg) in an attempt to correct her coagulation abnormality.Results. The patient's bleeding time was normalized with DDAVP administration, allowing her to receive epidural analgesia.Conclusions. Preeclampsia-induced platelet dysfunction might be corrected with DDAVP. A controlled study is required before its routine use can be advocated.