PT  - JOURNAL ARTICLE
AU  - Niño-Carreño, Claudia Stella
AU  - Puerta-Botero, Juan Esteban
AU  - Restrepo-Garces, Carlos Eduardo
TI  - #35519 Quadratus lumborum phenol neurolysis, an underrated alternative in malignancy
AID  - 10.1136/rapm-2023-ESRA.379
DP  - 2023 Sep 01
TA  - Regional Anesthesia & Pain Medicine
PG  - A207--A208
VI  - 48
IP  - Suppl 1
4099  - http://rapm.bmj.com/content/48/Suppl_1/A207.short
4100  - http://rapm.bmj.com/content/48/Suppl_1/A207.full
SO  - Reg Anesth Pain Med2023 Sep 01; 48
AB  - Please confirm that an ethics committee approval has been applied for or granted: Not relevant (see information at the bottom of this page)Background and Aims The analgesic cornerstone in cancer pain are opioids(1), in some cases interventional-pain-management is recommended(2). The Quadratus lumborum block(QLB) has shown benefits for abdominal wall(3), parietal and neuropathic pelvic pain(4). Its analgesic extends effect from T7-L1(5) this is explained by the relationship between the transverse fascia and the endothoracic fascia(6). Safety of phenolization has been described in cancer(7). We present a case report of QL2 phenolization for cancer pain.Methods This is a case of a 66-year-old male patient with malignant colonic cancer, metastatic to pancreas, spleen and abdominal wall, with intractable severe pain. A diagnostic QLB-2 was proposed because he refused any continuous neuraxial procedure. We proceeded under ultrasound-guide, in plane with a sham-rock approach, with 20mL bupivacaine 0.5% with 50 mg of triamcinolone (figure 1A). After 48 hours a neurolytic phenol injection was administered, with identical technique only bupivacaine was replaced by 20ml phenol 10%. (figure 1B).Results The patient’s reported 70% d dynamic and 80% on static decrease in pain on VAS for 48 hours and 42% oxycodone daily dose reduction with QL-2 block, 80% decrease in dynamic and 90% at rest pain during 10 days and 40% reduction in oxycodone dose with neurolysis. Unfortunately, due cluster symptoms he required intermittent sedation 2 weeks and past away.Abstract #35519 Figure 1 A: EOM: external oblique muscle, IOM internal oblique muscle, TM transverse muscle, QLM quadrates lumborum muscle. B: ultrasound guidance showing free liquid around needle tip. C: CT scan shows abdominal wall metastatic collectionsConclusions This case is a novel use for QLB-2 as an anatomical target for neurolytic procedures for abdominal cancer pain relief. Further trials are needed for to highlight the role of this procedure for a more widespread use.Attachment Phenol neurolysis QL-2.pdf