RT Journal Article SR Electronic T1 #34369 Quality of recovery after pericapsular nerve group (PENG) block for primary total hip arthroplasty under spinal anaesthesia JF Regional Anesthesia & Pain Medicine JO Reg Anesth Pain Med FD BMJ Publishing Group Ltd SP A279 OP A279 DO 10.1136/rapm-2023-ESRA.529 VO 48 IS Suppl 1 A1 Testón, Arturo Rodríguez A1 Forteza-Rey, Nicolás Ferrer A1 Pablo, Santiago Patterson A1 González, Elvira Pereda A1 Ricardo, Carregi Villegas A1 Violeta, Pérez Marí A1 Ibáñez, José De Andrés YR 2023 UL http://rapm.bmj.com/content/48/Suppl_1/A279.2.abstract AB Please confirm that an ethics committee approval has been applied for or granted: Not relevant (see information at the bottom of this page)Background and Aims The pericapsular nerve group (PENG) block is a novel regional anaesthesia technique that has been proposed as an effective motor-sparing block for total hip arthroplasty. Recent randomised studies show conflicting results regarding the analgesic efficacy of the PENG block for total hip arthroplastyMethods Randomised controlled observer-blinded single-centre superiority trial comparing the efficacy of the PENG block with no block for patients undergoing primary total hip arthroplasty under spinal anaesthesia. All subjects received multimodal analgesia consisting of paracetamol and celecoxib. The primary outcome was quality of recovery (QoR) at 24 h as measured by the QoR-15 questionnaireResults A total of 112 participants (56 in each group) were included in the analysis. The median (inter-quartile range [IQR]) 24-h QoR-15 scores were higher in subjects who received a PENG block (132 [116e138]) compared with subjects who did not (103 [97e112]) with a median difference of 26 (95% confidence interval, 18e31; P<0.001). Similarly, QoR-15 at 48 h was higher in the PENG group, and opioid use at 24 and 48 h postoperatively was significantly lower in the PENG group. However, we did not find significant differences in pain score, distance to ambulation, or anti-emetic use at any time point. We did not observe any PENG block-related complications.Abstract #34369 Figure 1 QoR-15 total by group and postoperative dayConclusions Adding a PENG block to a multimodal analgesia regimen that includes paracetamol and celecoxib improves the quality of recovery and reduces opioid requirements for patients undergoing primary total hip arthroplasty under spinal anaesthesia