Effects of tramadol via a µ-opioid receptor on pancreatic ductal adenocarcinoma in vitro and in vivo

Tomoya Kuramochi; Makoto Sano; Ichie Kajiwara; Yukino Oshima; Tomoaki Itaya; Jinsuk Kim; Yoshimi Ichimaru; Osamu Kitajima; Atsushi Masamune; Hideaki Ijichi; Takahiro Suzuki

doi:10.1136/rapm-2023-104511

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Effects of tramadol via a µ-opioid receptor on pancreatic ductal adenocarcinoma in vitro and in vivo

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Tomoya Kuramochi Department of Anesthesiology, Nihon University School of Medicine, Itabashi-ku, Tokyo, Japan PubMed articles Google scholar articles
Makoto Sano Department of Anesthesiology, Nihon University School of Medicine, Itabashi-ku, Tokyo, Japan PubMed articles Google scholar articles
Ichie Kajiwara Department of Anesthesiology, Nihon University School of Medicine, Itabashi-ku, Tokyo, Japan PubMed articles Google scholar articles
Yukino Oshima Department of Anesthesiology, Nihon University School of Medicine, Itabashi-ku, Tokyo, Japan PubMed articles Google scholar articles
Tomoaki Itaya Department of Anesthesiology, Nihon University School of Medicine, Itabashi-ku, Tokyo, Japan PubMed articles Google scholar articles
Jinsuk Kim Department of Anesthesiology, Nihon University School of Medicine, Itabashi-ku, Tokyo, Japan PubMed articles Google scholar articles
Yoshimi Ichimaru School of Pharmacy, Shonan University of Medical Sciences, Yokohama, Kanagawa, Japan PubMed articles Google scholar articles
Osamu Kitajima Department of Anesthesiology, Nihon University School of Medicine, Itabashi-ku, Tokyo, Japan PubMed articles Google scholar articles
Atsushi Masamune Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan PubMed articles Google scholar articles
Hideaki Ijichi Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, JapanClinical Nutrition Center, The University of Tokyo Hospital, Bunkyo-ku, Tokyo, Japan PubMed articles Google scholar articles
Takahiro Suzuki Department of Anesthesiology, Nihon University School of Medicine, Itabashi-ku, Tokyo, Japan PubMed articles Google scholar articles

Correspondence to Dr Makoto Sano, Department of Anesthesiology, Nihon University School of Medicine Department of Anesthesiology, Itabashi-ku 173-8610, Tokyo, Japan; sano.makoto{at}nihon-u.ac.jp

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Kuramochi T, Sano M, Kajiwara I, et al

Effects of tramadol via a µ-opioid receptor on pancreatic ductal adenocarcinoma in vitro and in vivo

Regional Anesthesia & Pain Medicine Published Online First: 23 June 2023. doi: 10.1136/rapm-2023-104511

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Received March 19, 2023
Accepted June 9, 2023
First published June 23, 2023.

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