Footnotes

• Contributors BMI first authored the manuscript with RAG's input and RAG revised the manuscript significantly.

• Funding Funding for this project provided by the Department of Anesthesiology, University of California San Diego, San Diego, California, USA. The contents of this editorial are solely the responsibility of the authors and do not necessarily represent the official views of this entity.

• Competing interests BMIs institution has received funding and/or product for his research from Myoscience, Epimed, Ferrosan Medical, Infutronics, Teleflex Medical, SPR Therapeutics, and Heron Therapeutics. RAG’s institution has received funding and/or product for his research from Myoscience, Epimed, Ferrosan Medical, Infutronics, and SPR Therapeutics.

• Patient consent for publication Not required.

• Provenance and peer review Commissioned; externally peer reviewed.