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Etidocaine Aerosol for Laryngotracheal Anesthesia Clinical Evaluation Using Exploratory Data Analysis
  1. Stuart R. Hameroff, MD,
  2. Juan Carlos Lerman, PhD and
  3. Casey D. Blitt, MD
  1. From the Department of Anesthesiology, University of Arizona College of Medicine, Arizona Health Sciences Center, Tucson, Arizona


Topical airway application of local anesthetics is used to blunt autonomic responses to intubation and to reduce coughing, bucking, and possible bronchospasm. In this study, laryngotracheal anesthesia (LTA) with etidocaine aerosol was evaluated. Techniques of Exploratory Data Analysis were used to illuminate the data and allow for interpretation of clinical relevance by the reader. Results indicate that etidocaine aerosol LTA blunted tachycardia response to intubation, 50 mg etidocaine appears to be the optimal dose, and etidocaine effects we observed are exerted topically rather than systemically.

  • Laryngotracheal anesthesia
  • Etidocaine
  • Aerosol
  • Exploratory data analysis

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