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Evaluation of Etidocaine Aerosol as a Topical Anesthetic
  1. Henry C. Johnston, MD, FFARCSI,
  2. Thresiamma Mukkada, MD and
  3. Phillip O. Bridenbaugh, MD
  1. From the Department of Anesthesia, University of Cincinnati College of Medicine, Cincinnati, Ohio

Abstract

The effects of 5% topical etidocaine aerosol applied to the larynx and tracheobronchial tree and its ability to attenuate the cardiovascular responses occurring after laryngoscopy and endotracheal anesthesia was studied in a double blind study in 60 patients who received either 5% etidocaine or placebo. The results of this study showed smaller rise in diastolic pressure in the etidocaine group (p < 0.025) as compared to placebo. There also appeared to be a greater rise in heart rate in the etidocaine group (p < 0.025) in response to spraying.

  • Anesthesia
  • endotracheal
  • topical
  • Etidocaine
  • aerosol
  • cardiac response
  • Laryngoscopy
  • topical anesthesia

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Footnotes

  • This study was supported by Astra Pharmaceutical Products, Inc.

    Address reprint requests to Dr. Johnston: Department of Anesthesia (531), University of Cincinnati College of Medicine, 231 Bethesda Avenue, Cincinnati, OH 45267.

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