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Abstract
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Background and Aims In addition to general anaesthesia, central and peripheral blocks are preferred for analgesia during pancreatic surgery. We aimed to investigate the effects of epidural and erector spinae plane (ESP) blocks on intraoperative and postoperative pain, renal function, and haemodynamic variables in patients undergoing Whipple surgery.
Methods The study participants were 65 ASAI-II-III patients aged 18–80 years who received general anaesthesia to undergo Whipple surgery. In the epidural group, a thoracic epidural block was performed at the appropriate level between T8 and T10 in 37 patients; a catheter was placed. In the ESP block group, a bilateral thoracic ESP block was performed with the administration of 0.25% bupivacaine (20 mL) on each side (50 mg bupivacaine) under ultrasonography guidance. Patients in this group received 50 mg of dexketoprofen before surgery. Pain scores and side effects were recorded at 0 min, 15 min, and 30 min postoperatively. The patients‘ intraoperative and 6 h, 12 h, and 24 h postoperative urine outputs; preoperative and 48 h postoperative creatinine levels; and 24 h postoperative systemic immune inflammation index (SII) values were recorded.
Results There was no statistically significant differences were noted between the groups in terms of demographic data. Hourly Ultiva consumption, VAS (visual analog scala) values, and creatine output levels were significantly higher in the ESP block group than in the epidural block group.
Distribution of analgesia characteristics according to groups
VAS distribution according to groups
Conclusions Epidural block reduced postoperative pain scores and intraoperative opioid consumption. We believe that the efficacy of the ESP block can be better evaluated using quality of life and recovery scores.